DIO1 Gene Polymorphism Is Associated with Thyroid Profiles and Reproductive Performance in Dairy Cows

Thyroid hormones mediate the interaction between metabolic and reproductive systems, while their metabolism is controlled by different deiodinases. The present study aimed to search for associations of cow genotypes with SNPs in deiodinase type 1 gene (DIO1) thyroid profiles traits. blood was sampled from Russian black-and-white cows 2–6 weeks before calving 1–13 after measure hormonal levels ELISA. RT-PCR analysis performed known mutations bovine DIO1 gene, a polymorphism at position 13,149 found. In animals CG genotype, concentration reverse triiodothyronine 6 prepartum higher decreased much earlier than CC genotype. Furthermore, week calving, total ratio genotype A proportion better values fertility traits revealed group compared group. Thus, more often have high ability, which may be associated rT3 profile features during early postpartum periods.